Search results for "model [particle]"
showing 10 items of 1261 documents
Investigation of insulin resistance in narcoleptic patients: dependent or independent of body mass index?
2011
Alice Engel1,2, Jana Helfrich1, Nina Manderscheid1, Petra B Musholt3, Thomas Forst3, Andreas Pfützner3, Norbert Dahmen1,21Department of Psychiatry, University of Mainz, Germany; 2Fachklinik Katzenelnbogen, Katzenelnbogen, Germany; 3IKFE, Institute for Clinical Research and Development, Mainz, GermanyBackground: Narcolepsy is a severe sleep-wake cycle disorder resulting in most cases from a lack of orexin, the energy balance-regulating hormone. Narcoleptic patients have been reported to suffer from an excess morbidity of Type 2 diabetes, even after correction for their often elevated body mass index.Methods: To explore whether narcolepsy is specifically associated with a propensity …
Melanin type and concentration determination using inverse model
2011
Abnormality of melanin production causes skin pigmentation disorders. Currently, assessment of treatment efficacy (under Physician's Global Assessment framework) only refers to visual conditions of skin surface and not the condition of the underlying skin layers and pigments. Albeit researches on models and simulations of light interaction with human skin have been reported, none has been specifically developed for pigmentation analysis of melanin types - eumelanin and pheomelanin. Therefore, our research objectives are to develop image analysis of skin pigmentation for classification and quantification of eumelanin and pheomelanin pigment types in human skin. In this research, the model is…
Quantitative Runge Approximation and Inverse Problems
2017
In this short note we provide a quantitative version of the classical Runge approximation property for second order elliptic operators. This relies on quantitative unique continuation results and duality arguments. We show that these estimates are essentially optimal. As a model application we provide a new proof of the result from \cite{F07}, \cite{AK12} on stability for the Calder\'on problem with local data.
Sequential and joint hydrogeophysical inversion using a field-scale groundwater model with ERT and TDEM data
2013
Abstract. Increasingly, ground-based and airborne geophysical datasets are used to inform groundwater models. Recent research focuses on establishing coupling relationships between geophysical and groundwater parameters. To fully exploit such information, this paper presents and compares a joint hydrogeophysical inversion (JHI) approach and sequential hydrogeophysical inversion (SHI) approach to inform a field-scale groundwater model with Time Domain Electromagnetic (TDEM) and Electrical Resistivity Tomography (ERT) data. The implemented SHI coupled inverted geophysical models with groundwater parameters, where the strength of the coupling was based on geophysical parameter resolution. To t…
Les connotacions ideològiques dels models lingüístics valencians: situació actual i condicionants històrics
2010
Estudi de les connotacions ideològiques dels models lingüístics presents en la comunitat de parla valenciana, a partir d’una selecció de variants lingüístiques sociològicament connotades, especialment de la transició ençà. El marc teoricometodològic emprat sorgeix de la combinació de l’anàlisi crítica del discurs amb la sociolingüística "latu sensu".
Effectuation Logic in Digital Business Model Transformation : Insights from Japanese High-Tech Innovators
2019
Purpose The purpose of this paper is to study how digital business models evolve when entrepreneurs move to new digital platforms and how this evolution is related to effectuation and causation logics. Design/methodology/approach This study applies a multiple case study approach to investigate how digital business models change in small, Japanese high-tech firms providing their innovations through different digital platforms. To investigate digital business models, this study considers the elements that comprise general business models. The case firms were selected based on size, products and transitions from physical to various digital platforms. Semi-structured interviews were conducted …
Thinking about industry decline : A qualitative meta-analysis and future research directions
2018
We analyze historical and longitudinal research focusing on industry decline. Our analysis suggests that the literature’s general reliance on a few meta-theoretical arguments has important consequences for how decline is framed and explained. We identify four meta-theoretical clusters in the literature: politics and market dynamics are seen as exogenous factors with deterministic features, whereas technology and management capabilities are framed as firm-internal failures with causally questionable explanations of how firm-level characteristics explain industry-level decline. We propose that it is important to understand the limitations of distinct meta-theoretical arguments for an enhanced…
Investing in strategic development : Management control of business model and managerial innovations
2018
Purpose This paper aims to explore management control in the strategic development of business model and managerial innovations. The issue is approached from the perspective of managerial work, aiming to outline what managers consider as essential elements of management control in these often iterative and learning-intensive developmental activities. Design/methodology/approach The study is based on the views of 20 managers engaged in strategic development and its control in various organisations. The interview data consist of the respondents’ experiences and project cases involving non-technological innovations. Qualitative content analysis is used to identify three key concepts of manage…
On a Robin (p,q)-equation with a logistic reaction
2019
We consider a nonlinear nonhomogeneous Robin equation driven by the sum of a \(p\)-Laplacian and of a \(q\)-Laplacian (\((p,q)\)-equation) plus an indefinite potential term and a parametric reaction of logistic type (superdiffusive case). We prove a bifurcation-type result describing the changes in the set of positive solutions as the parameter \(\lambda \gt 0\) varies. Also, we show that for every admissible parameter \(\lambda \gt 0\), the problem admits a smallest positive solution.
Filozofia jako ćwiczenie duchowe. Coachingowy model uprawiania filozofii
2018
Główną tezą tekstu jest uznanie tzw. modelu coachingowego za pierwotny i wciąż żywy sposób uprawiania filozofii. Twierdzę, że filozofia akademicka, która od kilku stuleci tkwi w tradycji scholastycznej, może być uprawiana w modelu coachingowym. W drugim paragrafie przedstawiam odróżnienie dwóch rodzajów filozofowania: Sokratejskiego – określonego w tekście mianem „coachingowego” – oraz Arystotelesowskiego, nazywanego tutaj „scholastycznym”. W trzecim paragrafie pokazuję, w jaki sposób Wiktor Frankl nawiązuje do coachingowej tradycji uprawiania filozofii w swojej praktyce terapeutycznej. W czwartym przedstawiam przykłady zastosowania modelu coachingowego w dydaktyce filozofii.